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CIALIS (TADALAFIL): USE IN SPECIAL POPULATIONS

Renal Insufficiency

Tadalafil (Cialis) tablets for Use as Needed

  • Mild (creatinine clearance 51 to 80 mL/min): No dose adjustment is required.
  • Moderate (creatinine clearance 31 to 50 mL/min): A starting dose of 5 mg not more than once per day is recommended, and the maximum dose should be limited to 10 mg not more than once in every 48 hours.
  • Severe (creatinine clearance < 30 mL/min and on hemodialysis): The maximum recommended dose is 5 mg not more than once in every 72 hours.

    Cialis for Once Daily Use

  • Mild (creatinine clearance 51 to 80 mL/min): No dose adjustment is required.
  • Moderate (creatinine clearance 31 to 50 mL/min): No dose adjustment is required.
  • Severe (creatinine clearance < 30 mL/min and on hemodialysis): Cialis tablets for once daily use is not recommended.

    Hepatic Impairment

    Tadalafil (Cialis) for Use as Needed

  • Mild or moderate (Child Pugh Class A or B): The dose of Cialis (Tadalafil) should not exceed 10 mg once per day. The use of Tadalafil (Cialis) tablets once per day has not been extensively evaluated in patients with hepatic insufficiency and therefore, caution is advised.
  • Severe (Child Pugh Class C): The use of Cialis is not recommended.

    Cialis tablets for Once Daily Use

  • Mild or moderate (Child Pugh Class A or B): Tadalafil (Cialis) for once daily use has not been extensively evaluated in patients with hepatic insufficiency. Therefore, caution is advised if Cialis (Tadalafil) for once daily use is prescribed to these patients.
  • Severe (Child Pugh Class C): The use of Tadalafil (Cialis) tablets is not recommended.

    Geriatrics

  • No dose adjustment is required in patients > 65 years of age.

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