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CIALIS (TADALAFIL): DOSAGE AND ADMINISTRATION

Erectile Dysfunction

Cialis for Use as Needed

  • The recommended starting dose of Cialis tablets for use as needed in most patients is 10 mg, taken prior to anticipated sexual activity.
  • The dose may be increased to 20 mg or decreased to 5 mg, based on individual efficacy and tolerability. The maximum recommended dosing frequency is once per day in most patients.
  • Tadalafil (Cialis) for use as needed was shown to improve erectile function compared to placebo up to 36 hours following dosing. Therefore, when advising patients on optimal use of Tadalafil (Cialis) tablets, this should be taken into consideration.

    Cialis for Once Daily Use

  • The recommended starting dose of Cialis tablets for once daily use is 2.5 mg, taken at approximately the same time every day, without regard to timing of sexual activity.
  • The Tadalafil (Cialis) dose for once daily use may be increased to 5 mg, based on individual efficacy and tolerability.

    Use with Food

    Cialis (Tadalafil) may be taken without regard to food.

    Concomitant Medications

    Nitrates

  • Concomitant use of nitrates in any form is contraindicated.

    Alpha Blockers

  • When Cialis is coadministered with an alpha blocker, patients should be stable on alpha-blocker therapy prior to initiating treatment with this medication, and Cialis tablets should be initiated at the lowest recommended dose.

    CYP3A4 Inhibitors

    Cialis (Tadalafil) tablets for Use as Needed

  • For patients taking concomitant potent inhibitors of CYP3A4, such as ketoconazole or ritonavir, the maximum recommended dose of Tadalafil (Cialis) is 10 mg, not to exceed once every 72 hours.

    Cialis (Tadalafil) for Once Daily Use

  • For patients taking concomitant potent inhibitors of CYP3A4, such as ketoconazole or ritonavir, the dose should not exceed 2.5 mg.

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